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The concomitant utilization of acetaminophen and codeine phosphate tablets with all cytochrome P450 3A4 inducers or discontinuation of the cytochrome P450 3A4 inhibitor may cause lessen codeine levels, increased norcodeine ranges, and fewer metabolism by using 2D6 with resultant reduced morphine concentrations.If concomitant use of a CYP3A4 inhibit